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human GNMT shRNA silencing Adenovirus

Name 
Ad-h-GNMT-shRNA
Cat No 
shADV-210131
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human GNMT.

shADV-210131
Ad-h-GNMT-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GNMT (glycine N-methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HEL-S-182mP
Description (Vector)
GNMT is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).
Gene ID
27232
Gene Name (Vector)
glycine N-methyltransferase
Gene Symbol
GNMT
HGNC ID
HGNC:4415
ORF Size (aa)
888
ORF Size (bp)
888 bp
RefSeq ID
NM_018960
RefSeq Synonyms
NM_018960, NM_001318865, BC032627,
Species
human
UniGene ID
Hs.144914

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.