mouse CLEC7A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Clec7a.
shAAV-255649
AAV-m-CLEC7A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Clec7a (C-type lectin domain family 7, member a). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
beta-GR; BGR; Clecsf12
Description (Vector)
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
Gene ID
56644
Gene Name (Vector)
C-type lectin domain family 7, member a
Gene Symbol
Clec7a
ORF Size (aa)
735
RefSeq ID
NM_020008
RefSeq Synonyms
NM_020008, NM_001309637, BC027742,
Species
mouse
UniGene ID
Mm.239516
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.