human CLEC7A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human CLEC7A.
shADV-205446
Ad-h-CLEC7A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human CLEC7A (C-type lectin domain family 7 member A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BGR; CANDF4; CD369; CLECSF12; DECTIN1; SCARE2
Description (Vector)
CLEC7A encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. CLEC7A is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
Gene ID
64581
Gene Name (Vector)
C-type lectin domain family 7 member A
Gene Symbol
CLEC7A
HGNC ID
HGNC:14558
ORF Size (aa)
399
ORF Size (bp)
399 bp
RefSeq ID
NM_022570
RefSeq Synonyms
NM_197954, NM_197950, NM_197949, NM_197948, NM_197947, NM_022570, BC071746,
Species
human
UniGene ID
Hs.143929
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.