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mouse CLEC7A Over-expression AAV

Name 
AAV-m-CLEC7A
Cat No 
AAV-255649
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Clec7a.

AAV-255649
AAV-m-CLEC7A

Ready-to-use AAV expressing Mouse Clec7a (C-type lectin domain family 7, member a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
beta-GR; BGR; Clecsf12
Description (Vector)
Lectin that functions as pattern receptor specific for beta-1,3-linked and beta-1,6-linked glucans, such as cell wall constituents from pathogenic bacteria and fungi. Necessary for the TLR2-mediated inflammatory response and for TLR2-mediated activation of NF-kappa-B. Enhances cytokine production in macrophages and dendritic cells. Mediates production of reactive oxygen species in the cell. Mediates phagocytosis of C.albicans conidia. Binds T-cells in a way that does not involve their surface glycans and plays a role in T-cell activation. Stimulates T-cell proliferation (By similarity).
Gene ID
56644
Gene Name (Vector)
C-type lectin domain family 7, member a
Gene Symbol
Clec7a
ORF Size (aa)
735
RefSeq ID
NM_020008
RefSeq Synonyms
NM_020008, NM_001309637, BC027742,
Species
mouse
UniGene ID
Mm.239516

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.