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mouse CDC2L1 shRNA silencing AAV

Name 
AAV-m-CDC2L1-shRNA
Cat No 
shAAV-255087
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cdk11b.

shAAV-255087
AAV-m-CDC2L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cdk11b (cyclin-dependent kinase 11B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA989746; Cdc11b; Cdc2l1; Cdc2l2; Cdk11; CDK11-p110; CDK11-p46; CDK11-p58; p58
Description (Vector)
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
Gene ID
12537
Gene Name (Vector)
cyclin-dependent kinase 11B
Gene Symbol
Cdk11b
ORF Size (aa)
2253
ORF Size (bp)
2253 bp
RefSeq ID
NM_007661
RefSeq Synonyms
NM_007661, NM_001347308, BC052920,
Species
mouse
UniGene ID
Mm.267410

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.