Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human CDK11B shRNA silencing Adenovirus

Name 
Ad-h-CDK11B-shRNA
Cat No 
shADV-204745
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CDK11B.

shADV-204745
Ad-h-CDK11B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CDK11B (cyclin-dependent kinase 11B). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CDC2L1; CDK11; CDK11-p110; CDK11-p46; CDK11-p58; CLK-1; FLJ59152; p58; p58CDC2L1; p58CLK-1; PK58;
Description (Vector)
CDK11B encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. CDK11B is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. CDK11B and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported.
Gene ID
984
Gene Name (Vector)
cyclin-dependent kinase 11B
Gene Symbol
CDK11B
HGNC ID
HGNC:1729
ORF Size (aa)
2349
ORF Size (bp)
2349 bp
RefSeq ID
NM_033493
RefSeq Synonyms
NM_033493, NM_033492, NM_033490, NM_033489, NM_033488, NM_033487, NM_033486, NM_001787, NM_001291345, BC171773, BC140714,
Species
human
UniGene ID
Hs.709182

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.