mouse CD47 shRNA silencing AAV

Name 
AAV-m-CD47-shRNA
Cat No 
shAAV-255016
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cd47.

shAAV-255016
AAV-m-CD47-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cd47 (CD47 antigen (Rh-related antigen, integrin-associated signal transducer)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9130415E20Rik; AA407862; AI848868; AW108519; B430305P08Rik; IAP; Itgp
Description (Vector)
Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.
Gene ID
16423
Gene Name (Vector)
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
Gene Symbol
Cd47
ORF Size (aa)
975
ORF Size (bp)
975 bp
RefSeq ID
NM_010581
RefSeq Synonyms
NM_010581, BC012667,
Species
mouse
UniGene ID
Mm.390865

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.