mouse BSND shRNA silencing AAV

Name 
AAV-m-BSND-shRNA
Cat No 
shAAV-254108
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Bsnd.

shAAV-254108
AAV-m-BSND-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Bsnd (Bartter syndrome, infantile, with sensorineural deafness (Barttin)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter.
Gene ID
140475
Gene Name (Vector)
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
Gene Symbol
Bsnd
ORF Size (aa)
924
ORF Size (bp)
924 bp
RefSeq ID
NM_080458
RefSeq Synonyms
NM_080458, BC038287,
Species
mouse
UniGene ID
Mm.135448

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.