human BSND shRNA silencing AAV

Name 
AAV-h-BSND-shRNA
Cat No 
shAAV-202301
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human BSND.

shAAV-202301
AAV-h-BSND-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human BSND (barttin CLCNK type accessory beta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BART; DFNB73
Description (Vector)
BSND encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness.
Gene ID
7809
Gene Name (Vector)
barttin CLCNK type accessory beta subunit
Gene Symbol
BSND
HGNC ID
HGNC:16512
ORF Size (aa)
963
ORF Size (bp)
963 bp
RefSeq ID
NM_057176
RefSeq Synonyms
NM_057176, BC103900, BC103899, BC103898,
Species
human
UniGene ID
Hs.151291

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.