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human UNC5C shRNA silencing AAV

Name 
AAV-h-UNC5C-shRNA
Cat No 
shAAV-227198
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human UNC5C.

shAAV-227198
AAV-h-UNC5C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human UNC5C (unc-5 netrin receptor C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
63
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
UNC5H3
Description (Vector)
UNC5C product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.
Gene ID
8633
Gene Name (Vector)
unc-5 netrin receptor C
Gene Symbol
UNC5C
HGNC ID
HGNC:12569
ORF Size (aa)
1794
ORF Size (bp)
1794 bp
RefSeq ID
NM_003728
RefSeq Synonyms
NM_003728, BC041156,
Species
human
UniGene ID
Hs.584831

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.