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mouse UNC5C shRNA silencing Adenovirus

Name 
Ad-m-UNC5C-shRNA
Cat No 
shADV-275638
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Unc5c.

shADV-275638
Ad-m-UNC5C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Unc5c (unc-5 netrin receptor C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B130051O18Rik; rcm; Unc5h3
Description (Vector)
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
Gene ID
22253
Gene Name (Vector)
unc-5 netrin receptor C
Gene Symbol
Unc5c
ORF Size (aa)
2853
ORF Size (bp)
2853 bp
RefSeq ID
NM_009472
RefSeq Synonyms
NM_009472, NM_001293561, BC115772,
Species
mouse
UniGene ID
Mm.24430

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.