mouse UNC5C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Unc5c.
shAAV-275638
AAV-m-UNC5C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Unc5c (unc-5 netrin receptor C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B130051O18Rik; rcm; Unc5h3
Description (Vector)
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity).
Gene ID
22253
Gene Name (Vector)
unc-5 netrin receptor C
Gene Symbol
Unc5c
ORF Size (aa)
2853
ORF Size (bp)
2853 bp
RefSeq ID
NM_009472
RefSeq Synonyms
NM_009472, NM_001293561, BC115772,
Species
mouse
UniGene ID
Mm.24430
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.