human SYNGR1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SYNGR1.
shAAV-224812
AAV-h-SYNGR1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SYNGR1 (synaptogyrin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
synaptogyrin-1
Description (eCommerce)
Synaptogyrin-1 is involved in the regulation of short-term and long-term synaptic plasticity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43759].
Description (Vector)
SYNGR1 encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified.
Gene ID
9145
Gene Name (eCommerce)
synaptogyrin 1
Gene Name (Vector)
synaptogyrin 1
Gene Symbol
SYNGR1
HGNC ID
HGNC:11498
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
576
Protein Name (eCommerce)
Synaptogyrin-1
RefSeq ID
NM_004711
RefSeq Synonyms
NM_145738, NM_145731, NM_004711, BC000731,
Research Areas
Neurobiology,Synapse
Research Areas (Faceted)
neurobiology
Species
human
Target Sentence
Synaptogyrin-1 is involved in the regulation of short-term and long-term synaptic plasticity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43759].
UniGene ID
Hs.216226
UniProt ID (eCommerce)
O43759
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.