human SLC39A6 shRNA silencing AAV

Name 
AAV-h-SLC39A6-shRNA
Cat No 
shAAV-223465
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SLC39A6.

shAAV-223465
AAV-h-SLC39A6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SLC39A6 (solute carrier family 39 member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
estrogen-regulated protein LIV-1; LIV-1; LIV-1 protein, estrogen regulated; solute carrier family 39 (metal ion transporter), member 6; solute carrier family 39 (zinc transporter), member 6; Solute carrier family 39 member 6; zinc transporter ZIP6; ZIP6; ZIP-6; zrt- and Irt-like protein 6
Description (eCommerce)
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]) [taken from NCBI Entrez Gene (Gene ID: 25800)].
Description (Vector)
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 (PubMed 12659941)).(supplied by OMIM, Mar 2008)
Gene ID
25800
Gene Name (eCommerce)
solute carrier family 39 member 6
Gene Name (Vector)
solute carrier family 39 member 6
Gene Symbol
SLC39A6
HGNC ID
HGNC:18607
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1302
Protein Name (eCommerce)
Zinc transporter ZIP6
RefSeq ID
NM_012319
RefSeq Synonyms
NM_012319, NM_001099406, BC039498,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]) [taken from NCBI Entrez Gene (Gene ID: 25800)].
UniGene ID
Hs.79136
UniProt ID (eCommerce)
Q13433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.