rat COLEC12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Colec12.
shAAV-293974
AAV-r-COLEC12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Colec12 (collectin sub-family member 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid beta in Alzheimer disease.
Gene ID
361289
Gene Name (Vector)
collectin sub-family member 12
Gene Symbol
Colec12
ORF Size (aa)
2229
ORF Size (bp)
2229 bp
RefSeq ID
NM_001025721
RefSeq Synonyms
NM_001025721, BC097495,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.