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human COLEC12 shRNA silencing Adenovirus

Name 
Ad-h-COLEC12-shRNA
Cat No 
shADV-205728
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human COLEC12.

shADV-205728
Ad-h-COLEC12-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human COLEC12 (collectin subfamily member 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CLP1; NSR2; SCARA4; SRCL
Description (Vector)
COLEC12 encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
Gene ID
81035
Gene Name (Vector)
collectin subfamily member 12
Gene Symbol
COLEC12
HGNC ID
HGNC:16016
ORF Size (aa)
2229
ORF Size (bp)
2229 bp
RefSeq ID
NM_130386
RefSeq Synonyms
NM_130386, BC060789,
Species
human
UniGene ID
Hs.464422

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.