human RS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human RS1.
shAAV-222025
AAV-h-RS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human RS1 (retinoschisin 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RS; XLRS1
Description (Vector)
RS1 encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision.
Gene ID
6247
Gene Name (Vector)
retinoschisin 1
Gene Symbol
RS1
HGNC ID
HGNC:10457
ORF Size (aa)
675
RefSeq ID
NM_000330
RefSeq Synonyms
NM_000330, BC141638, BC140343,
Species
human
UniGene ID
Hs.715725
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.