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human ESPN Over-expression AAV

Name 
AAV-h-ESPN
Cat No 
AAV-208111
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ESPN.

AAV-208111
AAV-h-ESPN

Ready-to-use AAV expressing Human ESPN (espin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DFNB36; LP2654
Description (Vector)
ESPN encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
Gene ID
83715
Gene Name (Vector)
espin
Gene Symbol
ESPN
HGNC ID
HGNC:13281
ORF Size (aa)
2565
ORF Size (bp)
2565 bp
RefSeq ID
NM_031475
RefSeq Synonyms
NM_031475, BC172457, BC156375,
Species
human
UniGene ID
Hs.147953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.