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human ESPN shRNA silencing Adenovirus

Name 
Ad-h-ESPN-shRNA
Cat No 
shADV-208112
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human ESPN.

shADV-208112
Ad-h-ESPN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ESPN (espin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DFNB36; LP2654
Description (Vector)
ESPN encodes a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells. Mutations in this gene are associated with autosomal recessive neurosensory deafness, and autosomal dominant sensorineural deafness without vestibular involvement.
Gene ID
83715
Gene Name (Vector)
espin
Gene Symbol
ESPN
HGNC ID
HGNC:13281
ORF Size (aa)
2565
ORF Size (bp)
2565 bp
RefSeq ID
NM_031475
RefSeq Synonyms
NM_031475, BC172457, BC156375,
Species
human
UniGene ID
Hs.147953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.