human RPGRIP1L shRNA silencing AAV

Name 
AAV-h-RPGRIP1L-shRNA
Cat No 
shAAV-221553
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human RPGRIP1L.

shAAV-221553
AAV-h-RPGRIP1L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human RPGRIP1L (RPGRIP1 like). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CORS3; FTM; JBTS7; MKS5; NPHP8; PPP1R134
Description (Vector)
RPGRIP1L can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 (JBTS7) and Meckel syndrome type 5 (MKS5). Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
23322
Gene Name (Vector)
RPGRIP1 like
Gene Symbol
RPGRIP1L
HGNC ID
HGNC:29168
ORF Size (aa)
3810
ORF Size (bp)
3810 bp
RefSeq ID
NM_001127897
RefSeq Synonyms
NM_015272, NM_001330538, NM_001328423, NM_001328422, NM_001308334, NM_001127897, BC136433,
Species
human
UniGene ID
Hs.298382

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.