human RPGRIP1L shRNA silencing Adenovirus

Name 
Ad-h-RPGRIP1L-shRNA
Cat No 
shADV-221553
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RPGRIP1L.

shADV-221553
Ad-h-RPGRIP1L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RPGRIP1L (RPGRIP1 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CORS3; FTM; JBTS7; MKS5; NPHP8; PPP1R134
Description (Vector)
RPGRIP1L can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 (JBTS7) and Meckel syndrome type 5 (MKS5). Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
23322
Gene Name (Vector)
RPGRIP1 like
Gene Symbol
RPGRIP1L
HGNC ID
HGNC:29168
ORF Size (aa)
3810
ORF Size (bp)
3810 bp
RefSeq ID
NM_001127897
RefSeq Synonyms
NM_015272, NM_001330538, NM_001328423, NM_001328422, NM_001308334, NM_001127897, BC136433,
Species
human
UniGene ID
Hs.298382

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.