human PTPLA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human HACD1.
shAAV-220301
AAV-h-PTPLA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human HACD1 (3-hydroxyacyl-CoA dehydratase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAP; PTPLA
Description (Vector)
PTPLA contains a characteristic catalytic motif of the protein tyrosine phosphatases (PTPs) family. The PTP motif of this protein has the highly conserved arginine residue replaced by a proline residue; thus it may represent a distinct class of PTPs. Members of the PTP family are known to be signaling molecules that regulate a variety of cellular processes. This gene was preferentially expressed in both adult and fetal heart. A much lower expression level was detected in skeletal and smooth muscle tissues, and no expression was observed in other tissues. The tissue specific expression in the developing and adult heart suggests a role in regulating cardiac development and differentiation.
Gene ID
9200
Gene Name (Vector)
3-hydroxyacyl-CoA dehydratase 1
Gene Symbol
HACD1
HGNC ID
HGNC:9639
ORF Size (aa)
867
RefSeq ID
NM_014241
RefSeq Synonyms
NM_014241, BC010353,
Species
human
UniGene ID
Hs.114062
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.