human PPBP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PPBP.
shAAV-219517
AAV-h-PPBP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PPBP (pro-platelet basic protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B-TG1; Beta-TG; CTAP-III; CTAP3; CTAPIII; CXCL7; LA-PF4; LDGF; MDGF; NAP-2; PBP; SCYB7; TC1; TC2; TGB; TGB1; THBGB; THBGB1
Description (Vector)
PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.
Gene ID
5473
Gene Name (Vector)
pro-platelet basic protein
Gene Symbol
PPBP
HGNC ID
HGNC:9240
ORF Size (aa)
387
RefSeq ID
NM_002704
RefSeq Synonyms
NM_002704, BC028217,
Species
human
UniGene ID
Hs.2164
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.