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human POLRMT shRNA silencing Adenovirus

Name 
Ad-h-POLRMT-shRNA
Cat No 
shADV-219427
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human POLRMT.

shADV-219427
Ad-h-POLRMT-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human POLRMT (RNA polymerase mitochondrial). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
APOLMT; h-mtRPOL; MTRNAP; MTRPOL
Description (Vector)
POLRMT encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.
Gene ID
5442
Gene Name (Vector)
RNA polymerase mitochondrial
Gene Symbol
POLRMT
HGNC ID
HGNC:9200
ORF Size (aa)
3693
ORF Size (bp)
3693 bp
RefSeq ID
NM_005035
RefSeq Synonyms
NM_005035, BC098387,
Species
human
UniGene ID
Hs.254113

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.