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mouse PPBP shRNA silencing AAV

Name 
AAV-m-PPBP-shRNA
Cat No 
shAAV-269126
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Ppbp.

shAAV-269126
AAV-m-PPBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Ppbp (pro-platelet basic protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2400003M24Rik; AI854500; b-TG1; beta-TG; CTAP3; CTAPIII; Cxcl7; LA-PF4; LDGF; MDGF; NAP-2; NAP-2-L1; Scyb7; TGB; TGB1; THBGB1
Description (Vector)
LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation.
Gene ID
57349
Gene Name (Vector)
pro-platelet basic protein
Gene Symbol
Ppbp
ORF Size (aa)
342
RefSeq ID
NM_023785
RefSeq Synonyms
NM_023785, BC127044, BC127043,
Species
mouse
UniGene ID
Mm.293614

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.