human ELF1 Over-expression AAV

Name 
AAV-h-ELF1
Cat No 
AAV-207832
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ELF1.

AAV-207832
AAV-h-ELF1

Ready-to-use AAV expressing Human ELF1 (E74 like ETS transcription factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E74-like factor 1; E74-like factor 1 (ets domain transcription factor); EFTUD1; ETS-related transcription factor Elf-1; RIA1
Description (eCommerce)
E74-like factor 1 (ELF1) is a member of the ETS (e26 transformation specific sequence) family of proteins, contains an ETS-domain, and shares sequence identity with the Drosophila ecdysone inducible E74 transcription factor. ETS was originally identified in the E26 retroviral isolate that led to the discovery of c-ets-1 (cellular ets-1), a cellular oncogenic transcription factor capable of transforming cells. Like ETS, ELF-1 functions as a transcription factor and has been shown to bind promoter and enhancer elements in a number of immunity responsive genes. ELF-1 is highly expressed in B-cells and appears to play an integral role in B-cell gene expression.
Description (Vector)
ELF1 encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.
Gene ID
1997
Gene Name (eCommerce)
E74 like ETS transcription factor 1
Gene Name (Vector)
E74 like ETS transcription factor 1
Gene Symbol
ELF1
HGNC ID
HGNC:3316
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1860
ORF Size (bp)
1860 bp
Protein Name (eCommerce)
ETS-related transcription factor Elf-1
RefSeq ID
NM_172373
RefSeq Synonyms
NM_172373, NM_001145353, BC030507,
Research Areas
Cardiovascular,Immunology,Interleukin Signaling,Signal Transduction,T-cell Receptor Signaling,Transcription Factor/Regulator
Research Areas (Faceted)
cardiovascular,cell_biology,immunology,signal_transduction,transcription_translation
Species
human
Target Sentence
E74-like factor 1 (ELF1) is a member of the ETS (e26 transformation specific sequence) family of proteins, contains an ETS-domain, and shares sequence identity with the Drosophila ecdysone inducible E74 transcription factor. ETS was originally identified in the E26 retroviral isolate that led to the discovery of c-ets-1 (cellular ets-1), a cellular oncogenic transcription factor capable of transforming cells. Like ETS, ELF-1 functions as a transcription factor and has been shown to bind promoter and enhancer elements in a number of immunity responsive genes. ELF-1 is highly expressed in B-cells and appears to play an integral role in B-cell gene expression.
UniGene ID
Hs.135646
UniProt ID (eCommerce)
P32519

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.