human MKL2 shRNA silencing AAV

Name 
AAV-h-MKL2-shRNA
Cat No 
shAAV-215500
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MKL2.

shAAV-215500
AAV-h-MKL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MKL2 (MKL1/myocardin like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTA-276F8.1; megakaryoblastic leukemia 2; MKL and myocardin family member 2; MKL/myocardin like 2; MKL/myocardin-like protein 2; MKL1/myocardin like 2; MKL2; MRTF-B; NPD001
Description (eCommerce)
Megakaryoblastic leukemia 2 (MKL2) is a transcriptional coactivator of serum response factor (SRF). MKL2 is required for skeletal myogenic differentiation.
Gene ID
57496
Gene Name (eCommerce)
myocardin related transcription factor B
Gene Name (Vector)
MKL1/myocardin like 2
Gene Symbol
MKL2
HGNC ID
HGNC:29819
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3300
ORF Size (bp)
3300 bp
Protein Name (eCommerce)
MKL/myocardin-like protein 2
RefSeq ID
NM_014048
RefSeq Synonyms
NM_014048, NM_001308142, BC171750, BC136260, BC047761,
Research Areas
Cell Biology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Megakaryoblastic leukemia 2 (MKL2) is a transcriptional coactivator of serum response factor (SRF). MKL2 is required for skeletal myogenic differentiation.
UniGene ID
Hs.49143
UniProt ID (eCommerce)
Q9ULH7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.