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human MAGI3 shRNA silencing AAV

Name 
AAV-h-MAGI3-shRNA
Cat No 
shAAV-214849
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAGI3.

shAAV-214849
AAV-h-MAGI3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAGI3 (membrane associated guanylate kinase, WW and PDZ domain containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
dJ730K3.2; MAGI-3; membrane-associated guanylate kinase inverted 3; membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3; membrane-associated guanylate kinase-related 3
Description (eCommerce)
The lengthily named membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 is encoded for by the gene MAGI3. This protein acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes [taken from UniProtKB (Entry: Q5TCQ9)].
Gene ID
260425
Gene Name (eCommerce)
membrane associated guanylate kinase, WW and PDZ domain containing 3
Gene Name (Vector)
membrane associated guanylate kinase, WW and PDZ domain containing 3
Gene Symbol
MAGI3
HGNC ID
HGNC:29647
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3378
ORF Size (bp)
3378 bp
Protein Name (eCommerce)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
RefSeq ID
NM_152900
RefSeq Synonyms
NM_152900, NM_001142782, BC130409,
Research Areas
Apoptosis,Host-Virus Interactions,JNK Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,infectious_disease,signal_transduction
Species
human
Target Sentence
The lengthily named membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 is encoded for by the gene MAGI3. This protein acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes [taken from UniProtKB (Entry: Q5TCQ9)].
UniGene ID
Hs.486189
UniProt ID (eCommerce)
Q5TCQ9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.