mouse MAGI3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Magi3.
shAAV-264124
AAV-m-MAGI3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Magi3 (membrane associated guanylate kinase, WW and PDZ domain containing 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4732496O19Rik; 6530407C02Rik; AA407180; AI120132; mKIAA1634
Description (Vector)
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
Gene ID
99470
Gene Name (Vector)
membrane associated guanylate kinase, WW and PDZ domain containing 3
Gene Symbol
Magi3
ORF Size (aa)
3378
ORF Size (bp)
3378 bp
RefSeq ID
NM_133853
RefSeq Synonyms
NM_133853, NM_001159354, BC156417,
Species
mouse
UniGene ID
Mm.264849
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.