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human SPCS2 shRNA silencing AAV

Name 
AAV-h-SPCS2-shRNA
Cat No 
shAAV-214349
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SPCS2.

shAAV-214349
AAV-h-SPCS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SPCS2 (signal peptidase complex subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
microsomal signal peptidase 25 kDa subunit; signal peptidase 25kDa subunit; signal peptidase complex subunit 2; signal peptidase complex subunit 2 homolog; SPase 25 kDa subunit
Description (eCommerce)
Signal peptidase complex subunit 2 (SPCS2) is a component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15005].
Gene ID
9789
Gene Name (eCommerce)
signal peptidase complex subunit 2
Gene Name (Vector)
signal peptidase complex subunit 2
Gene Symbol
SPCS2
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
681
ORF Size (bp)
681 bp
Protein Name (eCommerce)
Signal peptidase complex subunit 2
RefSeq ID
NM_014752
RefSeq Synonyms
NM_014752, BC106066, BC082231, BC070276, BC064957, BC008063,
Research Areas
Gene Expression,Metabolism/Metabolic Process,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Signal peptidase complex subunit 2 (SPCS2) is a component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15005].
UniGene ID
Hs.282700
UniProt ID (eCommerce)
Q15005

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.