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human TRPC6 Adenovirus

Name 
Ad-h-TRPC6
Cat No 
ADV-226546
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human TRPC6.

ADV-226546
Ad-h-TRPC6

Ready-to-use Adenovirus expressing Human TRPC6 (transient receptor potential cation channel subfamily C member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
focal segmental glomerulosclerosis 2; FSGS2; short transient receptor potential channel 6; transient receptor protein 6; TRP6; TRP-6; TrpC6
Description (eCommerce)
TRPC6 (transient receptor potential cation channel, subfamily C, member 6) forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in the TRPC6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) [taken from NCBI Entrez Gene (Gene ID: 7225].
Description (Vector)
TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Gene ID
7225
Gene Name (eCommerce)
transient receptor potential cation channel subfamily C member 6
Gene Name (Vector)
transient receptor potential cation channel subfamily C member 6
Gene Symbol
TRPC6
HGNC ID
HGNC:12338
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2796
ORF Size (bp)
2796 bp
Protein Name (eCommerce)
Short transient receptor potential channel 6
RefSeq ID
NM_004621
RefSeq Synonyms
NM_004621, BC093660, BC093658,
Research Areas
Axon Guidance,Cardiovascular,GPCR Signaling,Neurobiology,Signal Transduction,Transport
Research Areas (Faceted)
cardiovascular,signal_transduction,neurobiology,neurobiology,cell_biology
Species
human
Target Sentence
TRPC6 (transient receptor potential cation channel, subfamily C, member 6) forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in the TRPC6 gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) [taken from NCBI Entrez Gene (Gene ID: 7225].
UniGene ID
Hs.159003
UniProt ID (eCommerce)
Q9Y210

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.