human KCNN4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KCNN4.
shAAV-212769
AAV-h-KCNN4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KCNN4 (potassium calcium-activated channel subfamily N member 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DHS2; hIKCa1; hKCa4; hSK4; IK; IK1; IKCA1; KCa3.1; KCA4; SK4
Description (Vector)
KCNN4 is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
Gene ID
3783
Gene Name (Vector)
potassium calcium-activated channel subfamily N member 4
Gene Symbol
KCNN4
HGNC ID
HGNC:6293
ORF Size (aa)
1284
ORF Size (bp)
1284 bp
RefSeq ID
NM_002250
RefSeq Synonyms
NM_002250, BC015337,
Species
human
UniGene ID
Hs.10082
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.