human INSIG2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human INSIG2.
shAAV-212303
AAV-h-INSIG2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human INSIG2 (insulin induced gene 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
INSIG-2
Description (Vector)
INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
Gene ID
51141
Gene Name (Vector)
insulin induced gene 2
Gene Symbol
INSIG2
HGNC ID
HGNC:20452
ORF Size (aa)
678
RefSeq ID
NM_016133
RefSeq Synonyms
NM_016133, NM_001321333, NM_001321332, NM_001321331, NM_001321330, NM_001321329, BC022475,
Species
human
UniGene ID
Hs.7089
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.