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human DNAL1 shRNA silencing AAV

Name 
AAV-h-DNAL1-shRNA
Cat No 
shAAV-207182
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DNAL1.

shAAV-207182
AAV-h-DNAL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAL1 (dynein axonemal light chain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C14orf168; CILD16
Description (Vector)
DNAL1 encodes an axonemal dynein light chain which functions as a component of the outer dynein arms complex. This complex acts as the molecular motor that provides the force to move cilia in an ATP-dependent manner. The encoded protein is expressed in tissues with motile cilia or flagella and may be involved in the movement of sperm flagella. Alternate splicing results in multiple transcript variants.
Gene ID
83544
Gene Name (Vector)
dynein axonemal light chain 1
Gene Symbol
DNAL1
HGNC ID
HGNC:23247
ORF Size (aa)
456
RefSeq ID
NM_031427
RefSeq Synonyms
NM_031427, NM_001201366, BC005343,
Species
human
UniGene ID
Hs.525445

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.