human TPSD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TPSD1.
shADV-226302
Ad-h-TPSD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TPSD1 (tryptase delta 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MCP7-LIKE; MCP7L1; MMCP-7L
Description (Vector)
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein.
Gene ID
23430
Gene Name (Vector)
tryptase delta 1
Gene Symbol
TPSD1
HGNC ID
HGNC:14118
ORF Size (aa)
729
RefSeq ID
NM_012217
RefSeq Synonyms
NM_012217, BC069143,
Species
human
UniGene ID
Hs.677789
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.