human DDC Over-expression AAV

Name 
AAV-h-DDC
Cat No 
AAV-206697
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DDC.

AAV-206697
AAV-h-DDC

Ready-to-use AAV expressing Human DDC (dopa decarboxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AADC
Description (Vector)
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Gene ID
1644
Gene Name (Vector)
dopa decarboxylase
Gene Symbol
DDC
HGNC ID
HGNC:2719
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
RefSeq ID
NM_000790
RefSeq Synonyms
NM_001242890, NM_001242889, NM_001242888, NM_001242887, NM_001242886, NM_001082971, NM_000790, BC008366, BC000485,
Species
human
UniGene ID
Hs.359698

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.