human DDC shRNA silencing Adenovirus

Name
Ad-h-DDC-shRNA

Cat No
shADV-206697

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human DDC.

shADV-206697

Ad-h-DDC-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human DDC (dopa decarboxylase). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AADC

Description (Vector)

The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene ID

1644

Gene Name (Vector)

dopa decarboxylase

Gene Symbol

DDC

HGNC ID

HGNC:2719

ORF Size (aa)

1443

ORF Size (bp)

1443 bp

RefSeq ID

NM_000790

RefSeq Synonyms

NM_001242890, NM_001242889, NM_001242888, NM_001242887, NM_001242886, NM_001082971, NM_000790, BC008366, BC000485,

Species

human

UniGene ID

Hs.359698

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.