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human CASK shRNA silencing AAV

Name 
AAV-h-CASK-shRNA
Cat No 
shAAV-204106
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CASK.

shAAV-204106
AAV-h-CASK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CASK (calcium/calmodulin dependent serine protein kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAGH39; CAMGUK; CMG; FGS4; LIN2; MICPCH; MRXSNA; TNRC8
Description (Vector)
CASK encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
8573
Gene Name (Vector)
calcium/calmodulin dependent serine protein kinase
Gene Symbol
CASK
HGNC ID
HGNC:1497
ORF Size (aa)
2694
ORF Size (bp)
2694 bp
RefSeq ID
NM_003688
RefSeq Synonyms
NM_003688, NM_001126055, NM_001126054, BC143456, BC143454, BC117311,
Species
human
UniGene ID
Hs.495984

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.