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human CASK shRNA silencing Adenovirus

Name 
Ad-h-CASK-shRNA
Cat No 
shADV-204106
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human CASK.

shADV-204106
Ad-h-CASK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CASK (calcium/calmodulin dependent serine protein kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CAGH39; CAMGUK; CMG; FGS4; LIN2; MICPCH; MRXSNA; TNRC8
Description (Vector)
CASK encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
8573
Gene Name (Vector)
calcium/calmodulin dependent serine protein kinase
Gene Symbol
CASK
HGNC ID
HGNC:1497
ORF Size (aa)
2694
ORF Size (bp)
2694 bp
RefSeq ID
NM_003688
RefSeq Synonyms
NM_003688, NM_001126055, NM_001126054, BC143456, BC143454, BC117311,
Species
human
UniGene ID
Hs.495984

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.