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mouse CASK shRNA silencing AAV

Name 
AAV-m-CASK-shRNA
Cat No 
shAAV-254548
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Cask.

shAAV-254548
AAV-m-CASK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Cask (calcium/calmodulin-dependent serine protein kinase (MAGUK family)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DXPri1; DXRib1; LIN-2; mLin-2; Pals3
Description (Vector)
Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.
Gene ID
12361
Gene Name (Vector)
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Gene Symbol
Cask
ORF Size (aa)
2763
ORF Size (bp)
2763 bp
RefSeq ID
NM_009806
RefSeq Synonyms
NM_009806, NM_001284505, NM_001284504, NM_001284503, BC157057, BC148659, BC145620, BC141292,
Species
mouse
UniGene ID
Mm.474948

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.