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human CACNA1E shRNA silencing AAV

Name 
AAV-h-CACNA1E-shRNA
Cat No 
shAAV-203902
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CACNA1E.

shAAV-203902
AAV-h-CACNA1E-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CACNA1E (calcium voltage-gated channel subunit alpha1 E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BII; CACH6; CACNL1A6; Cav2.3; gm139
Description (Vector)
Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1, alpha-2, beta, and delta subunits in a 1:1:1:1 ratio. These channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This gene encodes the alpha-1E subunit of the R-type calcium channels, which belong to the 'high-voltage activated' group that maybe involved in the modulation of firing patterns of neurons important for information processing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
777
Gene Name (Vector)
calcium voltage-gated channel subunit alpha1 E
Gene Symbol
CACNA1E
HGNC ID
HGNC:1392
ORF Size (aa)
6813
ORF Size (bp)
6813 bp
RefSeq ID
NM_000721
RefSeq Synonyms
NM_001205294, NM_001205293, NM_000721, BC172376,
Species
human
UniGene ID
Hs.437444

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.