mouse CACNA1E shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Cacna1e.
shAAV-254363
AAV-m-CACNA1E-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Cacna1e (calcium channel, voltage-dependent, R type, alpha 1E subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A430040I15; alpha1E; BII; Cach6; Cacnl1a6; Cav2.3; Cchra1
Description (Vector)
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.
Gene ID
12290
Gene Name (Vector)
calcium channel, voltage-dependent, R type, alpha 1E subunit
Gene Symbol
Cacna1e
ORF Size (aa)
6822
ORF Size (bp)
6822 bp
RefSeq ID
NM_009782
RefSeq Synonyms
NM_009782, BC150750,
Species
mouse
UniGene ID
Mm.267517
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.