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human DTNB Adenovirus

Name 
Ad-h-DTNB
Cat No 
ADV-207373
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human DTNB.

ADV-207373
Ad-h-DTNB

Ready-to-use Adenovirus expressing Human DTNB (dystrobrevin beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
DTNB encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
1838
Gene Name (Vector)
dystrobrevin beta
Gene Symbol
DTNB
HGNC ID
HGNC:3058
ORF Size (aa)
1830
ORF Size (bp)
1830 bp
RefSeq ID
NM_021907
RefSeq Synonyms
NM_183361, NM_183360, NM_033148, NM_033147, NM_021907, NM_001320937, NM_001320936, NM_001320935, NM_001320934, NM_001320933, NM_001320932, NM_001256308, NM_001256304, NM_001256303, BC049366, BC016655,
Species
human
UniGene ID
Hs.307720

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.