human AURKC shRNA silencing AAV

Name 
AAV-h-AURKC-shRNA
Cat No 
shAAV-201836
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AURKC.

shAAV-201836
AAV-h-AURKC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AURKC (aurora kinase C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
Description (Vector)
AURKC encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. AURKC is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Gene ID
6795
Gene Name (Vector)
aurora kinase C
Gene Symbol
AURKC
HGNC ID
HGNC:11391
ORF Size (aa)
828
ORF Size (bp)
828 bp
RefSeq ID
NM_003160
RefSeq Synonyms
NM_003160, NM_001015879, NM_001015878, BC075064,
Species
human
UniGene ID
Hs.98338

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.