mouse AURKC Over-expression AAV

Name 
AAV-m-AURKC
Cat No 
AAV-280566
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Aurkc.

AAV-280566
AAV-m-AURKC

Ready-to-use AAV expressing Mouse Aurkc (aurora kinase C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AIE1; AIK3; ARK-3; IAK3; Stk13
Description (Vector)
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.
Gene ID
20871
Gene Name (Vector)
aurora kinase C
Gene Symbol
Aurkc
ORF Size (aa)
831
RefSeq ID
NM_020572
RefSeq Synonyms
NM_020572, NM_001080966, NM_001080965, BC064780,
Species
mouse
UniGene ID
Mm.261572

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.