rat MAPT shRNA silencing Adenovirus

Name 
Ad-r-MAPT-shRNA
Cat No 
shADV-295154
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Rat Mapt.

shADV-295154
Ad-r-MAPT-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Mapt (microtubule-associated protein tau). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Mtapt; pTau; RNPTAU; Tau
Description (Vector)
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Gene ID
29477
Gene Name (Vector)
microtubule-associated protein tau
Gene Symbol
Mapt
ORF Size (aa)
1032
ORF Size (bp)
1032 bp
RefSeq ID
NM_017212
RefSeq Synonyms
NM_017212, BC126095,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.