rat CYP1A2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Cyp1a2.
shADV-295068
Ad-r-CYP1A2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Cyp1a2 (cytochrome P450, family 1, subfamily a, polypeptide 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CYPD45; P-450d; RATCYPD45
Description (Vector)
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Gene ID
24297
Gene Name (Vector)
cytochrome P450, family 1, subfamily a, polypeptide 2
Gene Symbol
Cyp1a2
ORF Size (aa)
1542
ORF Size (bp)
1542 bp
RefSeq ID
NM_012541
RefSeq Synonyms
NM_012541, BC127476,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.