rat NMNAT1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Rat Nmnat1.
shADV-295057
Ad-r-NMNAT1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Rat Nmnat1 (nicotinamide nucleotide adenylyltransferase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.
Gene ID
298653
Gene Name (Vector)
nicotinamide nucleotide adenylyltransferase 1
Gene Symbol
Nmnat1
ORF Size (aa)
858
ORF Size (bp)
858 bp
RefSeq ID
NM_001037556
RefSeq Synonyms
NM_001037556, BC127446,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.