rat WDR77 shRNA silencing Adenovirus

Name
Ad-r-WDR77-shRNA

Cat No
shADV-294630

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Wdr77.

shADV-294630

Ad-r-WDR77-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Wdr77 (WD repeat domain 77). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

Ac2-269; MEP-50; RGD1310479

Description (Vector)

Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Gene ID

310769

Gene Name (Vector)

WD repeat domain 77

Gene Symbol

Wdr77

ORF Size (aa)

1029

ORF Size (bp)

1029 bp

RefSeq ID

NM_001008771

RefSeq Synonyms

NM_001008771, BC097367,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.