rat DIS3L shRNA silencing Adenovirus

Name
Ad-r-DIS3L-shRNA

Cat No
shADV-293716

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Dis3l.

shADV-293716

Ad-r-DIS3L-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Dis3l (DIS3-like exosome 3′-5′ exoribonuclease). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

RGD1308959

Description (Vector)

Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

Gene ID

363077

Gene Name (Vector)

DIS3-like exosome 3'-5' exoribonuclease

Gene Symbol

Dis3l

ORF Size (aa)

2916

ORF Size (bp)

2916 bp

RefSeq ID

NM_001008380

RefSeq Synonyms

NM_001008380, BC085932,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.